GCImagePresenter
a database on histological images of murine splenic germinal centers
Macrophages (CD68) 2
Proliferating cells (Ki-67)
FDC-network (FDC-M2)
Parameter Parameter description Calculation formula
D areat Total GC area [μm2]
D areat Total GC area [μm2]
D areaLZ Area of GC light zone [µm2]
D nKit Total number of Ki-67+ cells
D nKiLZ Number of Ki-67+ cells in GC light zone
D nTp+LZ Number of CD3+ Ki-67+ proliferating T cells in GC light zone
D nMLZ Number of CD68+ macrophages in GC light zone
D nMDZ Number of CD68+ macrophages in GC dark zone




d areaDZ Area of GC dark zone [µm2] = areat - areaLZ
d nKiDZ Number of Ki-67+ proliferating cells in GC dark zone = nKit - nKiLZ
d nMt Total number of CD68+ macrophages = nMLZ + nMDZ

D, direct quantity; d, derived quantity